Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is a common, multifaceted endocrinopathy associated with metabolic alterations such as insulin resistance, hyperinsulinemia, dyslipidemia, and obesity, and thereby an increased risk of developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Endothelial dysfunction and chronic inflammation are early findings in the atherosclerotic process. Elevated serum levels of uric acid may reflect low-grade chronic inflamm...

Background: Antiphospholipid syndrome (APS) is characterized by venous or arterial thrombosis and/or an adverse pregnancy outcome in the presence of persistent laboratory evidence of antiphospholipid antibodies. Loss of adrenal function due to bilateral adrenal vein thrombosis, resulting in hemorrhagic infarction, may occur in association with APS.Case presentation: We present the case of a 45-year-old woman with APS diagnosis since she was 37, with hist...

Background: Acromegaly is a rare endocrine disorder characterized by sustained hypersecretion of growth hormone (GH) with concomitant elevation of insulin-like growth factor I (IGF-I) associated with acral enlargement, sleep apnea, cardiovascular and metabolic disorders. Its annual incidence is approximately six per million people. The most common cause of acromegaly is a somatotroph (growth hormone-secreting) adenoma of the anterior pituitary.Methods: A...

Aims: Medullary thyroid carcinoma (MTC) is a rare endocrine cancer that accounts for approximately 5% of all thyroid cancers. Both the diagnosis and management of MTC could be difficult. Surgery is a main therapy in MTC, chemotherapy and external radiotherapy have limited efficacy. Recently, the relationship between some of the hemocytometer parameters and cancer has been investigated. In this study we aimed to determine the relationship between MTC and hemocytometer parameter...